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Bronchopulmonary Sequestration (BPS)

Bronchopulmonary sequestration (BPS), or pulmonary sequestration, is a condition in which one section of lung does not communicate with the normal lung tissue. Because the BPS is not connected to the normal lung, the BPS does not function in respiration (breathing). The blood supply of a BPS does not arise from the pulmonary blood supply.

BPS can be detected in a fetus by prenatal ultrasound. The lesion appears as an echogenic (bright) lobar or triangular shaped mass. It is usually seen in the lower left chest. Rarely a BPS can become relatively large and act as a space-occupying lesion within the fetal chest. This can result in underdevelopment of the lung tissue and lethal pulmonary hypoplasia, as well as compression of cardiovascular structures and eventual fetal hydrops (heart failure) and death.

Fetal treatment is indicated in cases of BPS complicated with hydrops (heart failure). In these cases, the feeding vessels that feed the BPS can be targeted and occluded via laser energy or sclerotherapy. The hydrops fetalis usually resolves in three to four weeks.


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Cole Landry's Story: 2009

The Landry family.

Dr. Ramen Chmait performed the the fourth successful procedure worldwide to shrink a congenital cystic adenomatiod malformation (CCAM), a mass of abnormal lung tissue, and release the pressure on Cole's heart thereby giving him a chance at surviving. Today Cole is a happy, smiling boy.

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Twin-Twin Transfusion Syndrome: 2007

LA Fetal Therapy is pioneering a new treatment for twin-twin transfusion syndrome, also known as TTTS, using laser energy to seal off the blood vessels that shunt blood between two fetuses that share the same placenta.

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Lower Urinary Tract Obstruction: 2008

Fetal lower urinary tract obstruction (LUTO) is a rare condition that is caused by a blockage of fetal urination. Because the baby cannot empty the bladder, the baby’s bladder subsequently becomes very large and distended. Learn more about what LA Fetal Therapy is doing to correct this fetal condition in utero.

learn more about acardiac twins